Ratty Corner

Health History of Brandywine Litters

Last modified: Saturday, 18-Oct-2014 19:02:34 BST but not completely up to date.

My rats do not always have perfect health throughout their lives. Their main worry is chronic respiratory disease, which seems to affect a few rats from each generation. Thankfully I have not bred down from any of those who subsequently developed this problem, so anticipate that the incidence will fall as time goes on. We have also had some mammary lumps on the females, but again those that I have bred down from have had them late in life (or not at all) and I hope to push this age back to the point where lumps do not occur during their lifetime.

Litter 2008/01: July 2008, Diggory x Kitty, 12 kittens

Inbreeding Coefficient: 0.0%

Parents:

Dam Kitty was doing well when I last heard towards the end of 2009, lifespan unknown at this point.

Sire Diggory died aged 31 months.

Kittens:

Sherbourne - HLD at 22 months. Died at 24 months with haemorrhage from ear.

Avon - SDAV at 8 months, died suddenly at 14 months cause unknown.

Cole - respiratory problems from 25 months. Put to sleep at 27 months with severe respiratory disease.

Blythe - Head tilt at 8 months from neck injury. Speyed to stop bleeding at 21 months. Neck tumour removed at 25 months. Put to sleep at 27 months with suspected brain tumour.

Arrow - Mammary lump removed at 25 months old. Put to sleep with internal tumour at 26 months.

Swift - Put to sleep at 18 months with abdominal tumour.

Kindred Spirit - Died aged 11 months from abscess-causing infection.

Poetic Justice - Died aged 14 months from abscess-causing infection.

Smartie - Put to sleep at 25 months with mammary tumour.

Waffle - Head tilt at 3 months. Put to sleep at 20 months due to undiagnosed illness following leg injury.

Arwen - Died suddenly at 19 months, cause unknown.

Galadriel - Put to sleep with a suspected brain tumour at 26 months.

This litter had a mean age of 21.32 months and a median age of 22.26, which is extremely disappointing and reflects the number of early deaths. Subsequent litters are already improving greatly on this.


Litter 2009/02: January 2009, Barnaby x Blythe, 14 kittens

Inbreeding Coefficient: 0.7%

Parents:

Sire Barnaby had a large abscess removed from his abdomen at 19 months old, and was put to sleep at 24 months old with a mass in his abdomen and an infection which appeared to have spread from a facial abscess into his brain.

Dam Blythe is the daughter of Diggory and Kitty. She suffered from a head tilt due to nerve damage caused by a nasty bite to the side of her neck during re-intros to her cage group after her litter. She was put to sleep at 27 months with a suspected brain tumour.

Kittens:

Kitinen - Died at 28 months of no obvious cause.

Aurajoki - Mammary lump removal at 23 months, pts at 28 months with severe uterine bleeding and major weight loss.

Janhijoki - Mammary lump removal at 14 months, head tilt at 21 months, died at 28 months of no obvious cause.

Kalajoki - Mammary lump removal at 16 months. Respiratory infection at 19 months, subsequently chronic. Second lump at 21 months. Put to sleep at 23 months due to respiratory issues - necropsy found abscessed lungs, suspected Corynebacterium kutscheri.

Merikarvianjoki - Wheezy on occasion from 21 months. HLD at 25 months, off his feet at put to sleep at 26 months.

Simojoki - Neutered at 18 months for hormonal aggression. Signs of hld at 24 months.

Tornionjoki - Ageing and losing weight at 21 months. Skeletal at 26 months and put to sleep suffering from respiratory distress.

Kirk - Very bad reaction to sutures at neutering at 18 months. Put to sleep at 21 months with respiratory disease.

Spock - Neck abscess at 16 months. Bad reaction to sutures on neutering at 18 months. Put to sleep at 29 months with HLD, lack of appetite and a nasty ear infection.

Lister - Died at 28 months during an op to investigate a wound.

Scratty - Died at 15 months, unknown cause.

Luigi - Put to sleep with suspected heart failure at 26 months.

Nancy Peanut - Died in Summer of 2010. Cause and date not provided.

Aisla Robertha - Healthy and doing well at 24 months. No recent update, so discounted in calculating litter lifespan.

None of this litter were bred from. The trimmed mean lifespan was 25.14 months and the median age of death was 26.71.


Litter 2009/03: June 2009, Sherbourne x Grace, 7 kittens

Inbreeding Coefficient: 0.0%

Parents:

Sire Sherbourne is the son of Diggory and Kitty. He was a lovely boy who has had no health problems through most of his life, but showed slight signs of hind leg degeneration at 22 months old and died two days before his second birthday.

Dam Grace comes from a line which has good resistance to respiratory infections, but some history of mammary lumps. She was born in June 2008 and had a tiny mammary lump removed at just under 26 months, living to just over three years. Grace is a really special rat who has passed her lovely temperament down to her descendants.

Kittens:

Wandle - Vaginal bleeding - spayed at 19 months. Put to sleep at 25 months with a facial tumour.

Effra - Slight wheeze at 16 months, responded to meds. Put to sleep with respiratory distress at 24 months.

Moselle - Slight wheeze at 16 months, responded to meds. Noisy breathing again at 21 months. Put to sleep at 26.5 months with respiratory distress.

Thames - Coat out of condition at 16 months. Wheezy at 17 months, subsequently chronic. Put to sleep at 21 months as he was struggling to breathe and was exhausted.

Tyburn - Tail kink. Testicular tumour at 20 months, died from complications following operation.

Brent - Slight rattle at 17 months, responded to meds. Put to sleep at 26 months as he couldn't breathe.

Ravensbourne - Put to sleep at 25.5 months after becoming immobile with bleeding from his ear after a week of leg weakness. Suspected undiagnosed ear infection.

This litter all caught an infection at 16 to 17 months. It didn't seem to be serious, and cleared up completely in all of the rats except Thames.

The mean lifespan for this litter was 24.23 months and the median age was 25.13. Most of them died/were put to sleep with respiratory problems.


Litter 2009/04: December 2009, Tyburn x Effra, 10 kittens

Inbreeding Coefficient: 26.2%

Because there is the possibility of a problem with the Diggory x Kitty litter and all my subsequent litters are descended from it, I've bred down only through Sherbourne. This has the dual effect of reducing the chance of the problem (if there is one) being passed down and also of testing for it.

Parents:

Sire Tyburn died at 20 months after an operation to remove a cancerous testicle, dam Effra was put to sleep at 24 months with respiratory disease.

Kittens:

Amber - No problems until 19.5 months, when she was found to have an inoperable uterine tumour and put to sleep.

Lea - Very slight respiratory noises on occasion. Respiratory problems due to allergy to fabric conditioner at 16.5 months. Put to sleep after severe weight loss at 17.5 months. PM found abscessed lungs, probably due to Corynebacterium Kutscheri.

Moss - Breathing slightly laboured after exercise from 16 months onwards. Losing some weight at 2 years. Suspect that she's managed to partially beat CK. Still going fairly well at 30 months old.

Derwent - Put to sleep with sudden severe breathing problems at 27.5 months.

Trent - Severe head tilt at 2 years. Intermittent ear infections until euthanised at 27 months for weight loss and continuing pain from ear.

Dante - Slight head tilt from one year onwards. Losing weight but still happy at 2 years.

Tesla - Dominant and bullying some cagemates. Very sadly died during spay to address behavioural problems. Swollen ovary, swollen uterus and pale liver.

Apollo - Noisy breathing most of the time, not serious. Not holding a good weight. Died at 17.5 months from respiratory problems.

Oscar - Respiratory problems at 2 years. Losing weight. Some HLD at 27 months. Put to sleep at 28 months after a long decline with breathing problems and HLD.

Samson - Inner ear infection at 16 months. Slight head tilt and weight loss. Died from ear haemorrhage at 16.5 months.

The lifespan for this litter is very widely spread, with several of them dying at an unacceptably young age but some continuing to a good old age. The mean age was 22.8 months and the median age was 23.18.


Litter 2009/05: December 2009, Tyburn x Wandle, 13 kittens

Inbreeding Coefficient: 26.2%

Wandle and Effra are sisters, so this litter is also checking against passing down any problems from my first litter.

Parents:

Sire Tyburn died at 20 months after an operation to remove a cancerous testicle, and dam Wandle lived to 25 months, when she was put to sleep with a facial tumour.

Kittens:

Amelie - Died at 23 months.

Domino - Died following a failed accidental pregnancy, age unknown.

Juno - Died at 23 months.

Nero - Died at 19 months.

Busby - Rattly on occasion. Suffered from continuing facial abscess and died at 29.5 months.

Mercury - Noisy breathing sometimes. Died at 17 months from respiratory disease.

Toulouse - Died at 20 months following chronic respiratory problems.

Bede - Died at 22 months with suspected kidney failure.

Lily - Infection at 10 weeks old. Recovered quickly with antibiotics. Died at 23 months.

Tilly - Infection at 10 weeks old. Put to sleep.

Mog - Mammary lump at 23 months. Put to sleep at 27 months with a mammary tumour.

Mitzy - Died suddenly at 23 months, cause unknown.

Rory - Respiratory infection at 10 months, then intermittent/ongoing, not responding to Baytril. Put to sleep at 18 months with worsening respiratory problems and swollen eye/haemorrhage.

This litter is doing very, very poorly. Only two of the twelve have reached two years old. Thankfully, for the line at least, I haven't bred down from them.

The mean lifespan for this litter was just 21 months, with the median being 23.08.


Litter 2010/06: April 2010, Ravensbourne x Effra, 8 kittens

Inbreeding Coefficient: 26.2%

Parents:

Sire Ravensbourne is completely healthy and has never shown any problems, and dam Effra was put to sleep at 24 months with a nasty respiratory infection. They are both from the Sherbourne x Grace litter.

Kittens:

Tamar - Spayed at 18 months following bleeding.

Dart - Healthy and doing well. Unexplained water retention at 24 months. Put to sleep at 25 months.

Torridge - rattly episode, responded quickly to meds. Put to sleep at 24 months due to a rectal growth.

Ashburn - Wheezy at 16 months. Chronic rattle from 22 months. Died unexpectedly at 26 months.

Culvery - Tail kink. Wheezy at 16 months. Chronic wheezing from 20 months. Put to sleep at 23.5 months with severe gasping and clicky lungs.

Otter - Neutered at almost 10 months for hormonal issues. Put to sleep at 22 months with severe gasping and clicky lungs.

Stoli - Died at 23 months.

Betty - Snuffles at 8 months, responded to antibiotics. Neck lump, treatment unsuccessful. Put to sleep at 10 months.

I managed to part with two of the does from this litter, but dithered long enough about which bucks to keep that I got too attached and kept all four.

The mean lifespan for this litter was 22.6 months with a median of 23.69.


Litter 2010/07: August 2010, Ravensbourne x Lea, 9 kittens

Inbreeding Coefficient: 26.2%

Parents:

Sire Ravensbourne and dam Lea were both completely healthy and had never shown any problems at the time of mating. Lea developed severe respiratory symptoms at 16.5 months and was put to sleep at 17 months. The PM revealed abscessed lungs consistent with Corynebacterium Kutscheri infection. Ravensbourne is from the Sherbourne x Grace litter, and Lea is his niece from the Tyburn x Effra litter.

Kittens:

Willow - Mammary lump at 10 months, probably triggered by having a litter. Wheezy at 16 months - cleared up quickly with meds. Healthy and well at 19 months. Put to sleep at 21.5 months with probably brain tumour.

Harper - Put to sleep at 18 months with a widespread abscess in his ear, jaw and back of his eye.

Cherwell - Wheezy at 17 months. Seemed to have cleared, but died unexpectedly overnight with bleeding from mouth and nose. PM revealed abscessed lungs.

Marley - Ageing but doing fairly well at 24 months. Fur thinning, having 'mini seizures' on occasion. No recent updates.

Pickle - Died unexpectedly at 21 months

Pan - No recent updates.

Poseidon - No recent updates.

Desire - No recent updates.

Delerium - No recent updates.

I didn't really get enough feedback on this litter to say how they did, although using the feedback from the four I did hear from gives a mean of 19.66 months and a median of 19.88. I'm fairly sure it would be higher if I had all the data.


Litter 2011/08: January 2011, Trent x Dart, 12 kittens

Inbreeding Coefficient: 32.1%

Parents:

Sire Trent was put to sleep at 27 months with a persistant ear infection and dam Dart is completely healthy and has never shown any problems. Trent is from the Tyburn x Effra litter, and Dart is his half sister from the Ravensbourne x Effra litter.

Kittens:

Mackenzie - Put to sleep at 23 months due to an inoperable ear tumour.

Logan - Put to sleep at 32 months with a probably zymbals gland tumour.

Annan - Very healthy, then some weight loss ending in an exceptionally quick decline with PT like symptoms. Put to sleep at 21 months.

Diamantina - Died at 16 months with unexplained gasping. Lungs and airways clear.

Darkling - Spayed for pyometra at 19 months. Died naturally at 31.5 months - had abdominal tumour.

RBA Essex girl - Died at 24 months.

R Silver Essex girl - Died at 22 months.

Barney - castrated for behavioural problems. Put to sleep at 29 months with blood in urine and laboured breathing.

Jonah - castrated for behavioural problems at 13 months. Put to sleep at 25.5 months with infected zymbals gland tumour.

Mikhail - Had diabetes, but this passed after a while. OK at 30 months.

Pipit - Zymbal's gland tumour. Put to sleep at 17 months

Ronald - Put to sleep at 21 months following progressive hld.

Lifespan is looking as if both mean and median will be around 24 months.


Litter 2011/09: January 2011, Derwent x Tamar, 11 kittens

Inbreeding Coefficient: 32.1%

Parents:

Sire Derwent died at 27.5 months with a sudden respiratory problem, and dam Tamar is very healthy although has been spayed for pyometra. Derwent is from the Tyburn x Effra litter, and Tamar is his half sister from the Sherbourne x Effra litter.

Kittens:

Fitzroy - Head tilt at 19 months. Put to sleep with a mouth tumour at 20 months.

Georgina - Neck abscess at 5 months. Neck abscess at 19 months.

Coral - Spayed at 21 months after heavy bleed. Polycystic right ovary and blood clots in the uterus. Losing weight and coordination at 29 months.

Lydia - recurring mammary lumps from 24 months.

Dorcas - having some sort of seizure at 18 months. Put to sleep at 19 months.

Agouti Essex girl - Died at 24 months.

Contra - spayed due to suspected pyo. Wheezy at 24 months.

Arrow - some wheeziness at 12 months. Continuing wheezes at 16 months. Losing weight and seeming 'out of it' at 20 months. Put to sleep with neurological symptoms.

Dandelion - Died at almost 27 months.

Hugo - recurring respiratory problems from 12 months. Put to sleep at 18 months.

Archie - diabetes from 15 months. Died at 18 months.

Some very young deaths, but also some older ones doing really well. The mean lifespan will again be around 24 months, but I'm not happy with so many early deaths.


Litter 2011/10: May 2011, Derwent x Willow, 17 kittens

Inbreeding Coefficient: 32.1%

Parents:

Sire Derwent died at 27.5 months with a sudden respiratory problem, dam Willow had a mammary lump shortly after her litter, probably triggered by the pregnancy hormones. She also had a wheezy spell at 16 months which cleared up quickly with meds. Derwent is from the Tyburn x Effra litter, and Willow is his cousin from the Ravensbourne x Lea litter.

Kittens:

Shansi - Died in her sleep at 27.5 months.

Cholet - Mammary lump at 29 months.

Quetta - Mammary lump at 27 months.

Alexandria - Mammary lumps removed at 20 months and 24 months. Two more lumps at 29 months.

Botany - Mammary lump removed at 20 months. Put to sleep with abdominal mass at 27.5 months.

Atlanta - Put to sleep with respiratory distress at 27 months.

Stepney - Died at 21.5 months after a very short respiratory illness.

Tomsk - Chronic respiratory problems from 21 months, died in his sleep at 27 months.

Tobermory - Died suddenly at 24 months with no obvious cause.

Twiglet - Tumour at 11 months, put to sleep at 12 months.

Acorn - Put to sleep at 18 months with a tumour.

Truffle - no problems.

Boris - Died unexpectedly at 17.5 months. Only symptom was unexplained biting.

Erik - Died at 13 months with probable diabetes.

George - Type 1 diabetes. Died at 23 months.

Bungle - Respiratory infection at 6 months. Doing well at 24 months.

Zippy - Died suddenly at 16 months.

Some unhappily early deaths, but also some long lives. It looks as if they'll come in close to 24 months mean yet again, but a higher median.


Litter 2011/11: May 2011, Ambrose x Dart, 8 kittens

Inbreeding Coefficient: 0.0%

Parents:

Sire Ambrose is suffering from HLD from 28 months, and dam Dart is completely healthy and has never shown any problems. Shunamite Ambrose is from Shunamite Rats, and Dart is unrelated and from the Ravensbourne x Effra litter.

Kittens:

Thessaly - Healthy and doing well at 29 months.

Heidelberg - Mammary lump removed at 25 months. Doing well at 29 months.

Alderney - Losing weight at 25 months. Died peacefully at 29 months.

Adelaide - Spayed for pyo at 18 months. Now very overweight but doing well at 29 months.

Wellington - Healthy and doing well at 29 months.

Bungo - Died at 26 months. No obvious cause. 'Old age'.

Orinoco - Losing weight at 25 months. Wheezy at 29 months.

Bulgaria - Losing weight at 29 months but seems well otherwise.

Looking really, really promising.


Litter 2011/12/L: November 2011, Hector x Diamantina, 12 kittens

Inbreeding Coefficient: 6.1%

Laurel - Healthy and doing well.

Lexington - Put to sleep at 14 months with neurological problems and throat lump making swallowing difficult.

Lincoln - Healthy and doing well.

Lola - Healthy and doing well.

Lucerne - Wheezy and with mammary lump at 19 months, put to sleep at 19 months with severe respiratory distress.

Pixie - 2 small lumps removed at 14 months - one fatty tissue, one mammary. More lumps at 20 months. Died following tumour removal op at 21 months.

Harmony - Healthy and doing well.

Jax - Healthy and doing well.

Opie - Healthy and doing well.

Freya - Healthy and doing well at 20 months.

Tig - Healthy and doing well.

Victory - Healthy and doing well.


Litter 2011/13/M: December 2011, Gabriel x Coral, 4 kittens

Inbreeding Coefficient: 6.1%

Marmion - Healthy and doing well at 22 months. Overweight.

Montrose - Lump under ear at 22 months.

Brandy - Died of unknown causes at 23 months.

Cointreau - Died of unknown causes at 23 months.


Litter 2012/14/O: March 2012, Logan x Shansi, 11 kittens

Inbreeding Coefficient: 34.4%

Oakley - Healthy and doing well.

Olympia - Healthy and doing well.

Opal - Healthy and doing well.

Oslo - Died suddenly at 12.5 months. No indication of what was wrong.

Echo - Died at 17.5 months with suspected pyometra.

Hetty - Lymphoma at 14 months.

Pebble - Healthy and doing well.

Shayla - Mammary lump removed at 19 months. Died of probable heart attack shortly after the operation.

Sierra - Possibly cancerous lump removed at 15 months.

Storm - Healthy and doing well.

Towie - Healthy and doing well.


Litter 2012/15/P: March 2012, Wellington x Heidelberg, 4 kittens

Inbreeding Coefficient: 28.3%

Phoenix - Healthy and doing well. Overweight.

Polly-wolly Doodle - Healthy and doing well.

Paddington - Healthy and doing well.

Parsnip - Died with enlarged liver at 8 months.


Litter 2012/16/R: July 2012, Hector x Marmion, 10 kittens

Inbreeding Coefficient: 20.7%

Ruby Slippers - Healthy and doing well.

River Mist - Healthy and doing well.

Rain Shadow - Healthy and doing well.

Ratilda - Healthy and doing well.

Rambling Rose - Healthy and doing well.

Ragdoll - Healthy and doing well.

Raffles - Healthy and doing well.

Rochester - Put to sleep at 15 months with a horrible infection eating through his jawbone.

Tertis - Healthy and doing well.

Schidlof - Healthy and doing well.


Litter 2012/17/T: December 2012, Olympia x Newton

Inbreeding Coefficient: 37.9%

Tansy - Healthy and doing well.

Thistle - Healthy and doing well.

Tiptoe - Healthy and doing well.

Tate - Healthy and doing well.

Teddy - Healthy and doing well.

Tiller - Healthy and doing well.

Sweetie - Healthy and doing well at 8 months.

Mollie - Healthy and doing well at 8 months.

Ritz - Healthy and doing well.

Ronnie - Healthy and doing well.

Rosie - Healthy and doing well.

Ben - Healthy and doing well.

Socrates - Healthy and doing well.


Litter 2013/18/U: March 2013, Rambling Rose (Bramble) x Quigley

Inbreeding Coefficient: 0.0%

Upsadaisy - Healthy and doing well.

Umami - Healthy and doing well.

Ulysses - Healthy and doing well.

Unanimous Boots - Healthy and doing well.

Gloves - Healthy and doing well.

Poodle - Healthy and doing well.

Cubit - Healthy and doing well.

Dittany - Healthy and doing well.

Bert - Healthy and doing well.

Ernie - Healthy and doing well.

Maisy - Healthy and doing well.

Susan - Healthy and doing well.


Litter 2013/19/V: March 2013, Ruby Slippers x Orinoco

Inbreeding Coefficient: 6.7%

Venus - Healthy and doing well.

Verity - Healthy and doing well.

Vector - Healthy and doing well.

Vortex - Healthy and doing well.

Elmo - Healthy and doing well.

Cookie - Healthy and doing well.

Penelope Pickle - Healthy and doing well.

Gerty - Healthy and doing well.

Bubbles - Healthy and doing well.

Lydia - Healthy and doing well.

Arya - Healthy and doing well.

Summary

I think we might be getting somewhere. Still too many early deaths and too many mammary lumps, but something's working.





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Last modified: Saturday, 18-Oct-2014 19:02:34 BST

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